Maintaining Order in Osteoporosis Treatments
نویسندگان
چکیده
منابع مشابه
Novel treatments for osteoporosis.
Osteoporosis is a major health problem that affects 4 to 6 million women and 1 to 2 million men in the US, with an even larger number of individuals having osteopenia or decreased bone mineral density (BMD) (1). The most significant consequence of osteoporosis is osteoporotic fractures, which in 1995 resulted in health care expenditures in the US of $13.8 billion (2). Consequently, the preventi...
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In the United States, an estimated 19% of older men and 30% of older women are at elevated risk of osteoporotic fracture and considered to be eligible for treatment. The burden of osteoporosis is similar in Europe and is projected to rise worldwide, with aging populations and increasing fracture rates accompanying urbanization. Notwithstanding its high prevalence, osteoporosis is often underdia...
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to fracture. However, bones fracture for different reasons, so there are several different biomechanical definitions of bone fragility. One function of bones is to carry loads. Fractures occur when loads exceed the bone strength, so weakened bones should be considered fragile. For example osteoporotic vertebral bodies might fracture during normal daily activities like opening a window or rising...
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Bisphosphonates are an important option for the prevention of fractures in postmenopausal women. However, the complex instructions for the administration of oral bisphosphonates are inconvenient or unsuitable for many patients, and adherence to long-term therapy is poor.1 The introduction of oral regimens for administration once weekly and, recently, once monthly has been associated with improv...
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High performance packet switches frequently use a centralized scheduler (also known as an arbiter) to determine the configuration of a non-blocking crossbar. The scheduler often limits the scalability of the system because of the frequency and complexity of its decisions. A recent paper by C.-S. Chang et al. introduces an interesting two-stage switch, in which each stage uses a trivial determin...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2017
ISSN: 0884-0431
DOI: 10.1002/jbmr.3127